Human SNP ID | rs314276 |
---|---|
Human chromosome | chr6 |
Human SNP position | 104960124 |
Pig chromosome | chr1 |
Pig SNP position | 80447558 |
PubMed ID | 19448623 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19448623 |
Study | Genetic variation in LIN28B is associated with the timing of puberty. |
Disease/Trait | Menarche (age at onset) |
Initial sample | 4,714 European ancestry female individuals |
Replication sample | 16,373 European ancestry female individuals |
Region | 6q16.3 |
Chromosome id | chr6 |
Chromosome position | 104960124 |
Reported gene | LIN28B |
Mapped gene | LIN28B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 389421 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs314276-C |
SNPs | rs314276 |
Merged | 0 |
SNP id current | 314276 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.67 |
P value | 0.0000000000000004 |
Pvalue mlog | 15.397940008672 |
P value text | |
Or beta | 0.14 |
%95 Ci | [0.11-0.17] year decrease |
Platform | Affymetrix [up to 390631] |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST000405 |
PubMed ID | 24770850 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24770850 |
Study | Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. |
Disease/Trait | Puberty onset |
Initial sample | 6,147 European ancestry girls, 3,769 European ancestry boys |
Replication sample | Up to 1,376 European ancestry individuals |
Region | 6q16.3 |
Chromosome id | chr6 |
Chromosome position | 104960124 |
Reported gene | LIN28B |
Mapped gene | LIN28B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 389421 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs314276-C |
SNPs | rs314276 |
Merged | 0 |
SNP id current | 314276 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.66 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.08 |
%95 Ci | [0.053-0.107] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | puberty onset measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005677 |
Study accession | GCST002425 |