Human SNP ID | rs3129900 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32338202 |
Pig chromosome | chr7 |
Pig SNP position | 28322763 |
PubMed ID | 20639878 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20639878 |
Study | A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. |
Disease/Trait | Lumiracoxib-related liver injury |
Initial sample | 31 European ancestry cases, 3 Hispanic cases, 1 case, 176 European, Hispanic and other ancestry controls |
Replication sample | 79 European ancestry cases, 16 Hispanic ancestry cases, 1 case, 405 European, Hispanic and other ancestry controls |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32338202 |
Reported gene | HLA-DRB1 |
Mapped gene | LOC101929163, C6orf10 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101929163, 10665 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3129900-? |
SNPs | rs3129900 |
Merged | 0 |
SNP id current | 3129900 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.105 |
P value | 7E-25 |
Pvalue mlog | 24.1549019599857 |
P value text | |
Or beta | 7.5 |
%95 Ci | [5.0-11.3] |
Platform | Affymetrix [682386] |
CNV | N |
Mapped trait | drug-induced liver injury |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004228 |
Study accession | GCST000735 |