SNP Detail For rs3129871
1.Mapping Information
Human SNP ID rs3129871
Human chromosome chr6
Human SNP position 32438565
Pig chromosome chr7
Pig SNP position 29034883
2.Annotation Information
PubMed ID23472185
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/23472185
StudyOligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.
Disease/TraitMultiple sclerosis (OCB status)
Initial sample1,367 European ancestry OCB positive cases, 161 European ancestry OCB negative cases
Replication sample3,029 European ancestry OCB positive cases, 374 European ancestry OCB negative cases
Region6p21.32
Chromosome idchr6
Chromosome position32438565
Reported geneHLA-DRA
Mapped geneBTNL2 - HLA-DRA
Upstream gene id56244
Downstream gene id3122
SNP gene ids
Upstream gene distance29686
Downstream gene distance1277
SNP risk allelers3129871-?
SNPsrs3129871
Merged0
SNP id current3129871
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000000000000006
Pvalue mlog14.2218487496163
P value text
Or beta1.72
%95 Ci[1.59-1.86]
PlatformIllumina [495970]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001891
PubMed ID23472185
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/23472185
StudyOligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.
Disease/TraitMultiple sclerosis (OCB status)
Initial sample1,367 European ancestry OCB positive cases, 161 European ancestry OCB negative cases, 428 European ancestry controls
Replication sampleNA
Region6p21.32
Chromosome idchr6
Chromosome position32438565
Reported geneHLA-DRA
Mapped geneBTNL2 - HLA-DRA
Upstream gene id56244
Downstream gene id3122
SNP gene ids
Upstream gene distance29686
Downstream gene distance1277
SNP risk allelers3129871-?
SNPsrs3129871
Merged0
SNP id current3129871
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.0000000000000001
Pvalue mlog16
P value text(OCB positive vs. controls)
Or beta1.98
%95 Ci[1.68-2.32]
PlatformIllumina [495970]
CNVN
Mapped traitmultiple sclerosis, oligoclonal band measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0005206
Study accessionGCST001892