SNP Detail For rs3125734
1.Mapping Information
Human SNP ID rs3125734
Human chromosome chr10
Human SNP position 62198353
Pig chromosome chr14
Pig SNP position 70775849
2.Annotation Information
PubMed ID23028356
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23028356
StudyFunctional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese.
Disease/TraitRheumatoid arthritis
Initial sample2,303 Japanese ancestry cases, 3,380 Japanese ancestry controls
Replication sample5,604 Japanese ancestry cases, 31,982 Japanese ancestry controls
Region10q21.2
Chromosome idchr10
Chromosome position62198353
Reported geneRTKN2
Mapped geneRTKN2
Upstream gene id
Downstream gene id
SNP gene ids219790
Upstream gene distance
Downstream gene distance
SNP risk allelers3125734-T
SNPsrs3125734
Merged0
SNP id current3125734
Contextmissense_variant
Intergenic0
Allele frequency0.108
P value0.000000005
Pvalue mlog8.30102999566398
P value text
Or beta1.2
%95 Ci[1.13-1.27]
PlatformIllumina [NR]
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST001681