Human SNP ID | rs3097645 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32985503 |
Pig chromosome | chr7 |
Pig SNP position | 29531906 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.873857556055831 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP16) |
Or beta | 0.2057 |
%95 Ci | [0.12-0.29] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.874157767431399 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (IGP2) |
Or beta | 0.2092 |
%95 Ci | [0.12-0.3] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.874270331235955 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP42) |
Or beta | 0.2151 |
%95 Ci | [0.13-0.3] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.873514573726542 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (IGP58) |
Or beta | 0.2131 |
%95 Ci | [0.12-0.3] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.87438328769575 |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | (IGP59) |
Or beta | 0.2057 |
%95 Ci | [0.12-0.3] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.873550828800713 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP61) |
Or beta | 0.206 |
%95 Ci | [0.12-0.3] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32985503 |
Reported gene | NR |
Mapped gene | BRD2 - HLA-DOA |
Upstream gene id | 6046 |
Downstream gene id | 3111 |
SNP gene ids | |
Upstream gene distance | 3998 |
Downstream gene distance | 18679 |
SNP risk allele | rs3097645-C |
SNPs | rs3097645 |
Merged | 0 |
SNP id current | 3097645 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.872971129118433 |
P value | 0.0000006 |
Pvalue mlog | 6.22184874961635 |
P value text | (IGP65) |
Or beta | 0.2253 |
%95 Ci | [0.14-0.31] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |