SNP Detail For rs3094188
1.Mapping Information
Human SNP ID rs3094188
Human chromosome chr6
Human SNP position 31174468
Pig chromosome chr7
Pig SNP position 27258521
2.Annotation Information
PubMed ID23266558
JournalGastroenterology
Linkwww.ncbi.nlm.nih.gov/pubmed/23266558
StudyA genome-wide association study identifies 2 susceptibility Loci for Crohn__s disease in a Japanese population.
Disease/TraitCrohn__s disease
Initial sample372 Japanese ancestry cases,3,389 Japanese ancestry controls
Replication sampleUp to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls
Region6p21.33
Chromosome idchr6
Chromosome position31174468
Reported genePSORS1C3
Mapped genePSORS1C3
Upstream gene id
Downstream gene id
SNP gene ids100130889
Upstream gene distance
Downstream gene distance
SNP risk allelers3094188-C
SNPsrs3094188
Merged0
SNP id current3094188
Contextintron_variant
Intergenic0
Allele frequency0.28
P value0.0000007
Pvalue mlog6.15490195998574
P value text
Or beta1.61
%95 Ci[1.33-1.94]
PlatformIllumina [4929034] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST001785
PubMed ID21801394
JournalOrphanet J Rare Dis
Linkwww.ncbi.nlm.nih.gov/pubmed/21801394
StudyGenome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.
Disease/TraitDrug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)
Initial sample424 European ancestry cases, 1,881 European ancestry controls
Replication sampleNA
Region6p21.33
Chromosome idchr6
Chromosome position31174468
Reported genePOU5F1
Mapped genePSORS1C3
Upstream gene id
Downstream gene id
SNP gene ids100130889
Upstream gene distance
Downstream gene distance
SNP risk allelers3094188-A
SNPsrs3094188
Merged0
SNP id current3094188
Contextintron_variant
Intergenic0
Allele frequency0.63
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta1.59
%95 Ci[1.34-1.88]
PlatformIllumina [268914]
CNVN
Mapped traitStevens-Johnson syndrome, toxic epidermal necrolysis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775
Study accessionGCST001181