Human SNP ID | rs3024493 |
---|---|
Human chromosome | chr1 |
Human SNP position | 206770623 |
Pig chromosome | chr9 |
Pig SNP position | 73760444 |
PubMed ID | 19915572 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19915572 |
Study | Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. |
Disease/Trait | Ulcerative colitis |
Initial sample | 2,361 European ancestry cases, 5,417 European ancestry controls |
Replication sample | 2,321 European ancestry cases, 4,818 European ancestry controls |
Region | 1q32.1 |
Chromosome id | chr1 |
Chromosome position | 206770623 |
Reported gene | IL10 |
Mapped gene | IL10 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3586 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3024493-? |
SNPs | rs3024493 |
Merged | 0 |
SNP id current | 3024493 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000008 |
Pvalue mlog | 7.09691001300805 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Affymetrix [NR] |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000527 |
PubMed ID | 20228798 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20228798 |
Study | Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). |
Disease/Trait | Ulcerative colitis |
Initial sample | 1,043 European ancestry cases, 1,703 European ancestry controls |
Replication sample | 2,539 European ancestry cases, 5,428 European ancestry controls |
Region | 1q32.1 |
Chromosome id | chr1 |
Chromosome position | 206770623 |
Reported gene | IL10 |
Mapped gene | IL10 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3586 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3024493-T |
SNPs | rs3024493 |
Merged | 0 |
SNP id current | 3024493 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.16 |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | |
Or beta | 1.35 |
%95 Ci | [1.22-1.50] |
Platform | Affymetrix [1897764] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000623 |
PubMed ID | 26192919 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Inflammatory bowel disease |
Initial sample | 12,882 European ancestry cases, 21,770 European ancestry controls |
Replication sample | 25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 1q32.1 |
Chromosome id | chr1 |
Chromosome position | 206770623 |
Reported gene | NR |
Mapped gene | IL10 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3586 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3024493-? |
SNPs | rs3024493 |
Merged | 0 |
SNP id current | 3024493 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 2E-50 |
Pvalue mlog | 49.698970004336 |
P value text | (EA) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | inflammatory bowel disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003767 |
Study accession | GCST003043 |
PubMed ID | 26502338 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26502338 |
Study | Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 5,201 European ancestry cases, 9,066 European ancestry controls |
Replication sample | NA |
Region | 1q32.1 |
Chromosome id | chr1 |
Chromosome position | 206770623 |
Reported gene | IL10 |
Mapped gene | IL10 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3586 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3024493-A |
SNPs | rs3024493 |
Merged | 0 |
SNP id current | 3024493 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.00000006 |
Pvalue mlog | 7.22184874961635 |
P value text | |
Or beta | 1.2 |
%95 Ci | [NR] |
Platform | Illumina [> 644674] (imputed) |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST003156 |