Human SNP ID | rs2941509 |
---|---|
Human chromosome | chr17 |
Human SNP position | 39764941 |
Pig chromosome | chr12 |
Pig SNP position | 23014591 |
PubMed ID | 26502338 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26502338 |
Study | Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 5,201 European ancestry cases, 9,066 European ancestry controls |
Replication sample | 2,018 European ancestry cases, 6,925 European ancestry controls |
Region | 17q12 |
Chromosome id | chr17 |
Chromosome position | 39764941 |
Reported gene | HER-2, C17orf37, GRB7, ZNFN1A3, ZBPB2, GSDMB, IKZF3, ERBB2 |
Mapped gene | IKZF3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 22806 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2941509-A |
SNPs | rs2941509 |
Merged | |
SNP id current | 2941509 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.000000008 |
Pvalue mlog | 8.09691001300805 |
P value text | |
Or beta | 1.35 |
%95 Ci | [1.22鈥?.49] |
Platform | Illumina [644674] |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST003155 |