SNP Detail For rs2941509
1.Mapping Information
Human SNP ID rs2941509
Human chromosome chr17
Human SNP position 39764941
Pig chromosome chr12
Pig SNP position 23014591
2.Annotation Information
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sample2,018 European ancestry cases, 6,925 European ancestry controls
Region17q12
Chromosome idchr17
Chromosome position39764941
Reported geneHER-2, C17orf37, GRB7, ZNFN1A3, ZBPB2, GSDMB, IKZF3, ERBB2
Mapped geneIKZF3
Upstream gene id
Downstream gene id
SNP gene ids22806
Upstream gene distance
Downstream gene distance
SNP risk allelers2941509-A
SNPsrs2941509
Merged
SNP id current2941509
Context3_prime_UTR_variant
Intergenic0
Allele frequency
P value0.000000008
Pvalue mlog8.09691001300805
P value text
Or beta1.35
%95 Ci[1.22鈥?.49]
PlatformIllumina [644674]
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003155