SNP Detail For rs2918307
1.Mapping Information
Human SNP ID rs2918307
Human chromosome chr19
Human SNP position 8679458
Pig chromosome chr2
Pig SNP position 71006888
2.Annotation Information
PubMed ID26482879
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26482879
StudyMulti-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls
Replication sample30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls
Region19p13.2
Chromosome idchr19
Chromosome position8679458
Reported geneADAMTS10, ACTL9
Mapped geneLOC105372267 - ACTL9
Upstream gene id105372267
Downstream gene id284382
SNP gene ids
Upstream gene distance1465
Downstream gene distance17939
SNP risk allelers2918307-G
SNPsrs2918307
Merged0
SNP id current2918307
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.16
P value0.000000000005
Pvalue mlog11.3010299956639
P value text(EA, fixed effects)
Or beta1.12
%95 Ci[1.08鈥?.16]
PlatformIllumina [15539996] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST003184