Human SNP ID | rs2902940 |
---|---|
Human chromosome | chr20 |
Human SNP position | 40462847 |
Pig chromosome | chr17 |
Pig SNP position | 48482195 |
PubMed ID | 20686565 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | LDL cholesterol |
Initial sample | 95,454 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40462847 |
Reported gene | MAFB |
Mapped gene | LOC105372618 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372618 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2902940-G |
SNPs | rs2902940 |
Merged | 0 |
SNP id current | 2902940 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.33 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | |
Or beta | 0.98 |
%95 Ci | [0.61-1.35] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000759 |
PubMed ID | 20686565 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | Cholesterol, total |
Initial sample | 100,184 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40462847 |
Reported gene | MAFB |
Mapped gene | LOC105372618 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372618 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2902940-G |
SNPs | rs2902940 |
Merged | 0 |
SNP id current | 2902940 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.29 |
P value | 0.00000000006 |
Pvalue mlog | 10.2218487496163 |
P value text | |
Or beta | 1.38 |
%95 Ci | [0.97-1.79] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST000760 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | LDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40462847 |
Reported gene | MAFB |
Mapped gene | LOC105372618 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372618 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2902940-G |
SNPs | rs2902940 |
Merged | 0 |
SNP id current | 2902940 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.3 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 0.027 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002222 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Cholesterol, total |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40462847 |
Reported gene | MAFB |
Mapped gene | LOC105372618 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372618 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2902940-G |
SNPs | rs2902940 |
Merged | 0 |
SNP id current | 2902940 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.3 |
P value | 0.0000000009 |
Pvalue mlog | 9.04575749056067 |
P value text | |
Or beta | 0.024 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST002221 |