SNP Detail For rs2897442
1.Mapping Information
Human SNP ID rs2897442
Human chromosome chr5
Human SNP position 132713335
Pig chromosome chr2
Pig SNP position 140492817
2.Annotation Information
PubMed ID22197932
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22197932
StudyMeta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample5,606 European ancestry cases, 20,565 European ancestry controls
Replication sample5,419 European ancestry cases, 19,833 European ancestry controls
Region5q31.1
Chromosome idchr5
Chromosome position132713335
Reported geneKIF3A
Mapped geneKIF3A
Upstream gene id
Downstream gene id
SNP gene ids11127
Upstream gene distance
Downstream gene distance
SNP risk allelers2897442-C
SNPsrs2897442
Merged0
SNP id current2897442
Contextintron_variant
Intergenic0
Allele frequency0.29
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta1.11
%95 Ci[1.07-1.15]
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST001363
PubMed ID26482879
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26482879
StudyMulti-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls
Replication sample30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls
Region5q31.1
Chromosome idchr5
Chromosome position132713335
Reported geneKIF3A
Mapped geneKIF3A
Upstream gene id
Downstream gene id
SNP gene ids11127
Upstream gene distance
Downstream gene distance
SNP risk allelers2897442-C
SNPsrs2897442
Merged0
SNP id current2897442
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000001
Pvalue mlog10
P value text(EA, fixed effects)
Or beta1.09
%95 Ci[1.06-1.12]
PlatformIllumina [15539996] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST003184