Human SNP ID | rs2894788 |
---|---|
Human chromosome | chr6 |
Human SNP position | 51778470 |
Pig chromosome | chr7 |
Pig SNP position | 52064490 |
PubMed ID | 23633212 |
---|---|
Journal | J Clin Endocrinol Metab |
Link | www.ncbi.nlm.nih.gov/pubmed/23633212 |
Study | Genome-wide association of single-nucleotide polymorphisms with weight loss outcomes after Roux-en-Y gastric bypass surgery. |
Disease/Trait | Weight loss (gastric bypass surgery) |
Initial sample | 86 European ancestry individuals with least EBWL, 89 European ancestry individuals with most EBWL |
Replication sample | 164 European ancestry individuals with least EBWL, 169 European ancestry individuals with most EBWL |
Region | 6p12.2, 6p12.3 |
Chromosome id | chr6;6;6;6;6;6 |
Chromosome position | 51809363;51778216;51790609;51778470;51808641;51791590 |
Reported gene | PKHD1 |
Mapped gene | PKHD1; PKHD1; PKHD1; PKHD1; PKHD1; PKHD1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1326589-?; rs728996-?; rs6458777-?; rs2894788-?; rs9296661-?; rs4715233-? |
SNPs | rs1326589; rs728996; rs6458777; rs2894788; rs9296661; rs4715233 |
Merged | 0 |
SNP id current | |
Context | intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant |
Intergenic | |
Allele frequency | 0.39 |
P value | 0.00000005 |
Pvalue mlog | 7.30102999566398 |
P value text | |
Or beta | 10.9 |
%95 Ci | unit decrease |
Platform | Affymetrix [730767] |
CNV | N |
Mapped trait | gastric bypass, body weight loss |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005244, http://www.ebi.ac.uk/efo/EFO_0005245 |
Study accession | GCST001985 |