Human SNP ID | rs2869966 |
---|---|
Human chromosome | chr4 |
Human SNP position | 88947927 |
Pig chromosome | chr8 |
Pig SNP position | 139567125 |
PubMed ID | 25241909 |
---|---|
Journal | Respir Res |
Link | www.ncbi.nlm.nih.gov/pubmed/25241909 |
Study | Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. |
Disease/Trait | Chronic obstructive pulmonary disease |
Initial sample | 3,777 European ancestry cases, 3,520 European ancestry smoker controls |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88947927 |
Reported gene | FAM13A |
Mapped gene | FAM13A, LOC105377327 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144, 105377327 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2869966-T |
SNPs | rs2869966 |
Merged | 0 |
SNP id current | 2869966 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.41 |
P value | 0.0000000007 |
Pvalue mlog | 9.15490195998574 |
P value text | |
Or beta | 1.29 |
%95 Ci | [1.19-1.40] |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | chronic obstructive pulmonary disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000341 |
Study accession | GCST002624 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1 |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88947927 |
Reported gene | FAM13A |
Mapped gene | FAM13A, LOC105377327 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144, 105377327 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2869966-T |
SNPs | rs2869966 |
Merged | 0 |
SNP id current | 2869966 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.55 |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | |
Or beta | 0.062 |
%95 Ci | NR unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume, response to bronchodilator |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 |
Study accession | GCST003262 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88947927 |
Reported gene | FAM13A |
Mapped gene | FAM13A, LOC105377327 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144, 105377327 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2869966-T |
SNPs | rs2869966 |
Merged | 0 |
SNP id current | 2869966 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.55 |
P value | 0.000000000002 |
Pvalue mlog | 11.698970004336 |
P value text | |
Or beta | 0.012 |
%95 Ci | unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003264 |