SNP Detail For rs285406
1.Mapping Information
Human SNP ID rs285406
Human chromosome chr8
Human SNP position 86012784
Pig chromosome chr4
Pig SNP position 55799369
2.Annotation Information
PubMed ID22379998
JournalPharmacogenomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22379998
StudyGenome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Disease/TraitAdverse response to lamotrigine and phenytoin
Initial sample34 European ancestry lamotrigine-induced hypersensitivity cases, 42 European ancestry phenytoin-induced hypersensitivity cases, 1,296 European ancestry controls
Replication sampleNA
Region8q21.3
Chromosome idchr8
Chromosome position86012784
Reported geneATP6V0D2
Mapped geneLOC105375622 - PSKH2
Upstream gene id105375622
Downstream gene id85481
SNP gene ids
Upstream gene distance151181
Downstream gene distance34325
SNP risk allelers285406-?
SNPsrs285406
Merged0
SNP id current285406
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000005
Pvalue mlog5.30102999566398
P value text(LTG)
Or beta
%95 Ci
PlatformIllumina [NR]
CNVN
Mapped traitresponse to anticonvulsant
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036277
Study accessionGCST001431