SNP Detail For rs28498264
1.Mapping Information
Human SNP ID rs28498264
Human chromosome chr15
Human SNP position 78545331
Pig chromosome chr7
Pig SNP position 52934142
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78545331
Reported genePSMA4
Mapped genePSMA4
Upstream gene id
Downstream gene id
SNP gene ids5685
Upstream gene distance
Downstream gene distance
SNP risk allelers28498264-T
SNPsrs28498264
Merged0
SNP id current28498264
Contextintron_variant
Intergenic0
Allele frequency0.212
P value0.00000000005
Pvalue mlog10.3010299956639
P value text
Or beta0.071
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78545331
Reported genePSMA4
Mapped genePSMA4
Upstream gene id
Downstream gene id
SNP gene ids5685
Upstream gene distance
Downstream gene distance
SNP risk allelers28498264-T
SNPsrs28498264
Merged0
SNP id current28498264
Contextintron_variant
Intergenic0
Allele frequency0.213
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.012
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264