Human SNP ID | rs28489187 |
---|---|
Human chromosome | chr1 |
Human SNP position | 85331427 |
Pig chromosome | chr4 |
Pig SNP position | 143197611 |
PubMed ID | 24159190 |
---|---|
Journal | Eur Heart J |
Link | www.ncbi.nlm.nih.gov/pubmed/24159190 |
Study | Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. |
Disease/Trait | Serum dimethylarginine levels (asymmetric/symetric ratio) |
Initial sample | 5110 European ancestry individuals |
Replication sample | NA |
Region | 1p22.3 |
Chromosome id | chr1 |
Chromosome position | 85331427 |
Reported gene | DDAH1 |
Mapped gene | DDAH1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 23576 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs28489187-G |
SNPs | rs28489187 |
Merged | 0 |
SNP id current | 28489187 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.216 |
P value | 1E-20 |
Pvalue mlog | 20 |
P value text | |
Or beta | 0.259 |
%95 Ci | [0.20-0.31] unit increase |
Platform | Affymetrix, Illumina [10085758] (imputed) |
CNV | N |
Mapped trait | serum dimethylarginine measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005418 |
Study accession | GCST002242 |
PubMed ID | 24159190 |
Journal | Eur Heart J |
Link | www.ncbi.nlm.nih.gov/pubmed/24159190 |
Study | Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. |
Disease/Trait | Asymmetrical dimethylarginine levels |
Initial sample | 5110 European ancestry individuals |
Replication sample | NA |
Region | 1p22.3 |
Chromosome id | chr1 |
Chromosome position | 85331427 |
Reported gene | DDAH1 |
Mapped gene | DDAH1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 23576 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs28489187-G |
SNPs | rs28489187 |
Merged | 0 |
SNP id current | 28489187 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.216 |
P value | 1E-40 |
Pvalue mlog | 40 |
P value text | |
Or beta | 0.37 |
%95 Ci | [0.32-0.42] unit increase |
Platform | Affymetrix, Illumina [10085758] (imputed) |
CNV | N |
Mapped trait | asymmetrical dimethylarginine measurement, serum dimethylarginine measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006522, http://www.ebi.ac.uk/efo/EFO_0005418 |
Study accession | GCST002241 |