Human SNP ID | rs2847281 |
---|---|
Human chromosome | chr18 |
Human SNP position | 12821594 |
Pig chromosome | chr6 |
Pig SNP position | 90250580 |
PubMed ID | 21300955 |
---|---|
Journal | Circulation |
Link | www.ncbi.nlm.nih.gov/pubmed/21300955 |
Study | Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. |
Disease/Trait | C-reactive protein levels |
Initial sample | 63,678 European ancestry individuals 1,792 Erasmus Ruchpen individuals, 715 Orcadian individuals |
Replication sample | 16,540 European ancestry individuals |
Region | 18p11.21 |
Chromosome id | chr18 |
Chromosome position | 12821594 |
Reported gene | PTPN2 |
Mapped gene | PTPN2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5771 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2847281-A |
SNPs | rs2847281 |
Merged | 0 |
SNP id current | 2847281 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.031 |
%95 Ci | [0.02-0.04] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST000965 |
PubMed ID | 22960999 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22960999 |
Study | Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. |
Disease/Trait | Esophageal cancer (squamous cell) |
Initial sample | 2,031 Han Chinese ancestry cases, 2,044 Han Chinese ancestry controls |
Replication sample | 8,092 Chinese ancestry cases, 8,620 Chinese ancestry controls |
Region | 18p11.21 |
Chromosome id | chr18 |
Chromosome position | 12821594 |
Reported gene | PTPN2 |
Mapped gene | PTPN2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5771 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2847281-C |
SNPs | rs2847281 |
Merged | 0 |
SNP id current | 2847281 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.16 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 1.2 |
%95 Ci | [1.14-1.26] |
Platform | NR [NR] |
CNV | N |
Mapped trait | squamous cell carcinoma, esophageal carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000707, http://www.ebi.ac.uk/efo/EFO_0002916 |
Study accession | GCST001674 |