SNP Detail For rs2847281
1.Mapping Information
Human SNP ID rs2847281
Human chromosome chr18
Human SNP position 12821594
Pig chromosome chr6
Pig SNP position 90250580
2.Annotation Information
PubMed ID21300955
JournalCirculation
Linkwww.ncbi.nlm.nih.gov/pubmed/21300955
StudyMeta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
Disease/TraitC-reactive protein levels
Initial sample63,678 European ancestry individuals 1,792 Erasmus Ruchpen individuals, 715 Orcadian individuals
Replication sample16,540 European ancestry individuals
Region18p11.21
Chromosome idchr18
Chromosome position12821594
Reported genePTPN2
Mapped genePTPN2
Upstream gene id
Downstream gene id
SNP gene ids5771
Upstream gene distance
Downstream gene distance
SNP risk allelers2847281-A
SNPsrs2847281
Merged0
SNP id current2847281
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta0.031
%95 Ci[0.02-0.04] unit increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitC-reactive protein measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004458
Study accessionGCST000965
PubMed ID22960999
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22960999
StudyGenome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
Disease/TraitEsophageal cancer (squamous cell)
Initial sample2,031 Han Chinese ancestry cases, 2,044 Han Chinese ancestry controls
Replication sample8,092 Chinese ancestry cases, 8,620 Chinese ancestry controls
Region18p11.21
Chromosome idchr18
Chromosome position12821594
Reported genePTPN2
Mapped genePTPN2
Upstream gene id
Downstream gene id
SNP gene ids5771
Upstream gene distance
Downstream gene distance
SNP risk allelers2847281-C
SNPsrs2847281
Merged0
SNP id current2847281
Contextintron_variant
Intergenic0
Allele frequency0.16
P value0.00000000002
Pvalue mlog10.698970004336
P value text
Or beta1.2
%95 Ci[1.14-1.26]
PlatformNR [NR]
CNVN
Mapped traitsquamous cell carcinoma, esophageal carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000707, http://www.ebi.ac.uk/efo/EFO_0002916
Study accessionGCST001674