Human SNP ID | rs2840044 |
---|---|
Human chromosome | chr17 |
Human SNP position | 35565049 |
Pig chromosome | chr12 |
Pig SNP position | 41455009 |
PubMed ID | 24785509 |
---|---|
Journal | Radiother Oncol |
Link | www.ncbi.nlm.nih.gov/pubmed/24785509 |
Study | A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. |
Disease/Trait | Response to radiotherapy in cancer (late toxicity) |
Initial sample | 579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases |
Replication sample | 516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases |
Region | 17q12 |
Chromosome id | chr17 |
Chromosome position | 35565049 |
Reported gene | SLFN14 |
Mapped gene | SLFN14 - RPL39P32 |
Upstream gene id | 342618 |
Downstream gene id | 100131387 |
SNP gene ids | |
Upstream gene distance | 4213 |
Downstream gene distance | 1411 |
SNP risk allele | rs2840044-? |
SNPs | rs2840044 |
Merged | 0 |
SNP id current | 2840044 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.33 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | (Breast cancer, overal toxicity, multivariable analysis) |
Or beta | 1.56 |
%95 Ci | |
Platform | Illumina [2417493] (imputed) |
CNV | N |
Mapped trait | response to radiation, breast carcinoma |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST002431 |