Human SNP ID | rs2839186 |
---|---|
Human chromosome | chr21 |
Human SNP position | 46270154 |
Pig chromosome | chr13 |
Pig SNP position | 218475881 |
PubMed ID | 23666240 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23666240 |
Study | Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. |
Disease/Trait | Testicular germ cell tumor |
Initial sample | 986 European ancestry cases, 4,946 European ancestry controls |
Replication sample | 1,064 European ancestry cases, 10,082 European ancestry controls |
Region | 21q22.3 |
Chromosome id | chr21 |
Chromosome position | 46270154 |
Reported gene | MCM3AP |
Mapped gene | MCM3AP |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8888 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2839186-T |
SNPs | rs2839186 |
Merged | 0 |
SNP id current | 2839186 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.46 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.26 |
%95 Ci | [1.15-1.38] |
Platform | Illumina [307291] |
CNV | N |
Mapped trait | testicular carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005088 |
Study accession | GCST002022 |
PubMed ID | 25877299 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25877299 |
Study | Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor. |
Disease/Trait | Testicular germ cell tumor |
Initial sample | 1,326 European ancestry cases, 6,687 European ancestry controls |
Replication sample | 710 European ancestry case-parent triads, 289 European ancestry cases, 290 European ancestry controls |
Region | 21q22.3 |
Chromosome id | chr21 |
Chromosome position | 46270154 |
Reported gene | MCM3AP |
Mapped gene | MCM3AP |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8888 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2839186-T |
SNPs | rs2839186 |
Merged | 0 |
SNP id current | 2839186 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.443 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 1.23 |
%95 Ci | [NR] |
Platform | Illumina [610240] |
CNV | N |
Mapped trait | Testicular Germ Cell Tumor |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_1000566 |
Study accession | GCST002855 |