SNP Detail For rs2814778
1.Mapping Information
Human SNP ID rs2814778
Human chromosome chr1
Human SNP position 159204893
Pig chromosome chr4
Pig SNP position 99222919
2.Annotation Information
PubMed ID22037903
JournalHum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22037903
StudyGenetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.
Disease/TraitWhite blood cell count
Initial sample12,046 European ancestry individuals, 1,487 African ancestry individuals
Replication sampleNA
Region1q23.2
Chromosome idchr1
Chromosome position159204893
Reported geneDARC
Mapped geneACKR1
Upstream gene id
Downstream gene id
SNP gene ids2532
Upstream gene distance
Downstream gene distance
SNP risk allelers2814778-A
SNPsrs2814778
Merged0
SNP id current2814778
Context5_prime_UTR_variant
Intergenic0
Allele frequency0.18
P value7E-55
Pvalue mlog54.1549019599857
P value text(AA)
Or beta1.35
%95 Ci[1.19-1.51] K/ul increase
PlatformIllumina [532566]
CNVN
Mapped traitleukocyte count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004308
Study accessionGCST001302
PubMed ID21507922
JournalClin Infect Dis
Linkwww.ncbi.nlm.nih.gov/pubmed/21507922
StudyDuffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
Disease/TraitNeutrophil count
Initial sample115 African ancestry HIV-negative individuals
Replication sampleNA
Region1q23.2
Chromosome idchr1
Chromosome position159204893
Reported geneDARC
Mapped geneACKR1
Upstream gene id
Downstream gene id
SNP gene ids2532
Upstream gene distance
Downstream gene distance
SNP risk allelers2814778-?
SNPsrs2814778
Merged0
SNP id current2814778
Context5_prime_UTR_variant
Intergenic0
Allele frequencyNR
P value0.00000001
Pvalue mlog8
P value text
Or beta
%95 Ci
PlatformIllumina [874956]
CNVN
Mapped traitneutrophil count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004833
Study accessionGCST001059
PubMed ID25884002
JournalOpen Forum Infect Dis
Linkwww.ncbi.nlm.nih.gov/pubmed/25884002
StudyPhenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.
Disease/TraitNeutrophil count in HIV-infection
Initial sample2,547 individuals
Replication sampleNA
Region1q23.2
Chromosome idchr1
Chromosome position159204893
Reported geneMPTX, DARC, CADM3
Mapped geneACKR1
Upstream gene id
Downstream gene id
SNP gene ids2532
Upstream gene distance
Downstream gene distance
SNP risk allelers2814778-C
SNPsrs2814778
Merged0
SNP id current2814778
Context5_prime_UTR_variant
Intergenic0
Allele frequency0.31
P value0.00000000000000003
Pvalue mlog16.5228787452803
P value text
Or beta0.11156583
%95 Ci[NR] unit decrease
PlatformIllumina [5954294] (imputed)
CNVN
Mapped traitneutrophil count, HIV-1 infection
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0000180
Study accessionGCST002743