Human SNP ID | rs2814778 |
---|---|
Human chromosome | chr1 |
Human SNP position | 159204893 |
Pig chromosome | chr4 |
Pig SNP position | 99222919 |
PubMed ID | 22037903 |
---|---|
Journal | Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22037903 |
Study | Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network. |
Disease/Trait | White blood cell count |
Initial sample | 12,046 European ancestry individuals, 1,487 African ancestry individuals |
Replication sample | NA |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159204893 |
Reported gene | DARC |
Mapped gene | ACKR1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2532 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2814778-A |
SNPs | rs2814778 |
Merged | 0 |
SNP id current | 2814778 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.18 |
P value | 7E-55 |
Pvalue mlog | 54.1549019599857 |
P value text | (AA) |
Or beta | 1.35 |
%95 Ci | [1.19-1.51] K/ul increase |
Platform | Illumina [532566] |
CNV | N |
Mapped trait | leukocyte count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004308 |
Study accession | GCST001302 |
PubMed ID | 21507922 |
Journal | Clin Infect Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/21507922 |
Study | Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. |
Disease/Trait | Neutrophil count |
Initial sample | 115 African ancestry HIV-negative individuals |
Replication sample | NA |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159204893 |
Reported gene | DARC |
Mapped gene | ACKR1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2532 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2814778-? |
SNPs | rs2814778 |
Merged | 0 |
SNP id current | 2814778 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [874956] |
CNV | N |
Mapped trait | neutrophil count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004833 |
Study accession | GCST001059 |
PubMed ID | 25884002 |
Journal | Open Forum Infect Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/25884002 |
Study | Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols. |
Disease/Trait | Neutrophil count in HIV-infection |
Initial sample | 2,547 individuals |
Replication sample | NA |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159204893 |
Reported gene | MPTX, DARC, CADM3 |
Mapped gene | ACKR1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2532 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2814778-C |
SNPs | rs2814778 |
Merged | 0 |
SNP id current | 2814778 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.31 |
P value | 0.00000000000000003 |
Pvalue mlog | 16.5228787452803 |
P value text | |
Or beta | 0.11156583 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [5954294] (imputed) |
CNV | N |
Mapped trait | neutrophil count, HIV-1 infection |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0000180 |
Study accession | GCST002743 |