SNP Detail For rs2808382
1.Mapping Information
Human SNP ID rs2808382
Human chromosome chr1
Human SNP position 211918606
Pig chromosome chr9
Pig SNP position 144413274
2.Annotation Information
PubMed ID25187353
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25187353
StudyClozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Disease/TraitClozapine-induced agranulocytosis
Initial sample161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls
Replication sampleNA
Region1q32.3
Chromosome idchr1
Chromosome position211918606
Reported geneINTS7
Mapped geneLOC102723727 - INTS7
Upstream gene id102723727
Downstream gene id25896
SNP gene ids
Upstream gene distance66191
Downstream gene distance21793
SNP risk allelers2808382-C
SNPsrs2808382
Merged0
SNP id current2808382
Contextregulatory_region_variant
Intergenic1
Allele frequency0.0469
P value0.000008
Pvalue mlog5.09691001300805
P value text
Or beta2.7742
%95 Ci[2.33-3.22]
PlatformIllumina [8809853] (imputed)
CNVN
Mapped traitdrug-induced agranulocytosis, response to clozapine
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338
Study accessionGCST002595