Human SNP ID | rs2808382 |
---|---|
Human chromosome | chr1 |
Human SNP position | 211918606 |
Pig chromosome | chr9 |
Pig SNP position | 144413274 |
PubMed ID | 25187353 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25187353 |
Study | Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Disease/Trait | Clozapine-induced agranulocytosis |
Initial sample | 161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls |
Replication sample | NA |
Region | 1q32.3 |
Chromosome id | chr1 |
Chromosome position | 211918606 |
Reported gene | INTS7 |
Mapped gene | LOC102723727 - INTS7 |
Upstream gene id | 102723727 |
Downstream gene id | 25896 |
SNP gene ids | |
Upstream gene distance | 66191 |
Downstream gene distance | 21793 |
SNP risk allele | rs2808382-C |
SNPs | rs2808382 |
Merged | 0 |
SNP id current | 2808382 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.0469 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | |
Or beta | 2.7742 |
%95 Ci | [2.33-3.22] |
Platform | Illumina [8809853] (imputed) |
CNV | N |
Mapped trait | drug-induced agranulocytosis, response to clozapine |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 |
Study accession | GCST002595 |