Human SNP ID | rs2788612 |
---|---|
Human chromosome | chr1 |
Human SNP position | 111873741 |
Pig chromosome | chr4 |
Pig SNP position | 118659531 |
PubMed ID | 24785509 |
---|---|
Journal | Radiother Oncol |
Link | www.ncbi.nlm.nih.gov/pubmed/24785509 |
Study | A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. |
Disease/Trait | Response to radiotherapy in cancer (late toxicity) |
Initial sample | 579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases |
Replication sample | 516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases |
Region | 1p13.2 |
Chromosome id | chr1 |
Chromosome position | 111873741 |
Reported gene | KCND3 |
Mapped gene | KCND3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3752 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2788612-? |
SNPs | rs2788612 |
Merged | 0 |
SNP id current | 2788612 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.05 |
P value | 0.0000000000000006 |
Pvalue mlog | 15.2218487496163 |
P value text | (Prostate cancer, rectal incontinence, univariable analysis) |
Or beta | 0.18 |
%95 Ci | [NR] unit increase |
Platform | Illumina [2417493] (imputed) |
CNV | N |
Mapped trait | response to radiation, prostate carcinoma |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001663 |
Study accession | GCST002431 |