SNP Detail For rs2788612
1.Mapping Information
Human SNP ID rs2788612
Human chromosome chr1
Human SNP position 111873741
Pig chromosome chr4
Pig SNP position 118659531
2.Annotation Information
PubMed ID24785509
JournalRadiother Oncol
Linkwww.ncbi.nlm.nih.gov/pubmed/24785509
StudyA genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
Disease/TraitResponse to radiotherapy in cancer (late toxicity)
Initial sample579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases
Replication sample516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases
Region1p13.2
Chromosome idchr1
Chromosome position111873741
Reported geneKCND3
Mapped geneKCND3
Upstream gene id
Downstream gene id
SNP gene ids3752
Upstream gene distance
Downstream gene distance
SNP risk allelers2788612-?
SNPsrs2788612
Merged0
SNP id current2788612
Contextintron_variant
Intergenic0
Allele frequency0.05
P value0.0000000000000006
Pvalue mlog15.2218487496163
P value text(Prostate cancer, rectal incontinence, univariable analysis)
Or beta0.18
%95 Ci[NR] unit increase
PlatformIllumina [2417493] (imputed)
CNVN
Mapped traitresponse to radiation, prostate carcinoma
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST002431