SNP Detail For rs275380
1.Mapping Information
Human SNP ID rs275380
Human chromosome chr12
Human SNP position 43536193
Pig chromosome chr5
Pig SNP position 77468137
2.Annotation Information
PubMed ID22379998
JournalPharmacogenomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22379998
StudyGenome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Disease/TraitAdverse response to lamotrigine and phenytoin
Initial sample34 European ancestry lamotrigine-induced hypersensitivity cases, 42 European ancestry phenytoin-induced hypersensitivity cases, 1,296 European ancestry controls
Replication sampleNA
Region12q12
Chromosome idchr12
Chromosome position43536193
Reported geneADAMTS20
Mapped geneADAMTS20
Upstream gene id
Downstream gene id
SNP gene ids80070
Upstream gene distance
Downstream gene distance
SNP risk allelers275380-?
SNPsrs275380
Merged0
SNP id current275380
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text(LTG)
Or beta
%95 Ci
PlatformIllumina [NR]
CNVN
Mapped traitresponse to anticonvulsant
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036277
Study accessionGCST001431