Human SNP ID | rs27524 |
---|---|
Human chromosome | chr5 |
Human SNP position | 96766240 |
Pig chromosome | chr2 |
Pig SNP position | 107114872 |
PubMed ID | 20953190 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20953190 |
Study | A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. |
Disease/Trait | Psoriasis |
Initial sample | 2,178 European ancestry cases, 5,175 European ancestry controls |
Replication sample | 3,174 European ancestry cases, 5,464 European ancestry controls |
Region | 5q15 |
Chromosome id | chr5 |
Chromosome position | 96766240 |
Reported gene | ERAP1 |
Mapped gene | ERAP1, CAST |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51752, 831 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs27524-A |
SNPs | rs27524 |
Merged | 0 |
SNP id current | 27524 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.36 |
P value | 0.00000000003 |
Pvalue mlog | 10.5228787452803 |
P value text | |
Or beta | 1.13 |
%95 Ci | [1.05-1.22] |
Platform | Illumina [535475] |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST000833 |
PubMed ID | 22286212 |
Journal | J Natl Cancer Inst |
Link | www.ncbi.nlm.nih.gov/pubmed/22286212 |
Study | Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups. |
Disease/Trait | Hodgkin__s lymphoma |
Initial sample | 1,200 European ancestry cases, 6,417 European ancestry controls |
Replication sample | 563 European ancestry cases, 613 European ancestry controls |
Region | 5q15 |
Chromosome id | chr5 |
Chromosome position | 96766240 |
Reported gene | ERAP1 |
Mapped gene | ERAP1, CAST |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51752, 831 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs27524-? |
SNPs | rs27524 |
Merged | 0 |
SNP id current | 27524 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | (Total cHL) |
Or beta | 1.22 |
%95 Ci | [1.11-1.33] |
Platform | Illumina [502514] |
CNV | N |
Mapped trait | Hodgkins lymphoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000183 |
Study accession | GCST001387 |
PubMed ID | 25574825 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25574825 |
Study | Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms. |
Disease/Trait | Psoriasis |
Initial sample | 4,212 European ancestry cases, 8,032 European ancestry controls |
Replication sample | NA |
Region | 5q15 |
Chromosome id | chr5 |
Chromosome position | 96766240 |
Reported gene | ERAP1 |
Mapped gene | ERAP1, CAST |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51752, 831 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs27524-A |
SNPs | rs27524 |
Merged | 0 |
SNP id current | 27524 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 1.195 |
%95 Ci | [1.157-1.234] |
Platform | Affymetrix, Illumina, Perlegen [up to 5493100] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002738 |