Human SNP ID | rs2727270 |
---|---|
Human chromosome | chr11 |
Human SNP position | 61835765 |
Pig chromosome | chr2 |
Pig SNP position | 9126837 |
PubMed ID | 24823311 |
---|---|
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24823311 |
Study | Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. |
Disease/Trait | Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) |
Initial sample | 8,631 European ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61835765 |
Reported gene | FTH1, INCENP, FADS1, FADS2, SCGB1D1, SCGB2A1, C11orf9, DAGLA, FEN1, RAB3IL, C11orf10, FADS3, SYT7, BEST1, SCGB1D2 |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2727270-T |
SNPs | rs2727270 |
Merged | 0 |
SNP id current | 2727270 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.44 |
P value | 3E-21 |
Pvalue mlog | 20.5228787452803 |
P value text | (Conditioned on rs174547) |
Or beta | 0.69 |
%95 Ci | [0.55-0.83] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | omega-6 polyunsaturated fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005680 |
Study accession | GCST002446 |
PubMed ID | 25646338 |
Journal | Am J Clin Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/25646338 |
Study | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Trans fatty acid levels |
Initial sample | 8,013 European ancestry individuals |
Replication sample | 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61835765 |
Reported gene | NR |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2727270-T |
SNPs | rs2727270 |
Merged | 0 |
SNP id current | 2727270 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.1209 |
P value | 0.000000007 |
Pvalue mlog | 8.15490195998574 |
P value text | (Cis/trans-18:2, EA) |
Or beta | 0.0038 |
%95 Ci | [0.0026-0.005] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cis/trans-18:2 fatty acid measurement, trans fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821 |
Study accession | GCST002721 |