Human SNP ID | rs2720499 |
---|---|
Human chromosome | chr8 |
Human SNP position | 17534848 |
Pig chromosome | chr17 |
Pig SNP position | 5696236 |
PubMed ID | 26031901 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/26031901 |
Study | Genome-wide association study of leukotriene modifier response in asthma. |
Disease/Trait | Response to zileuton treatment in asthma (FEV1 change interaction) |
Initial sample | 160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases |
Replication sample | 149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases |
Region | 8p22 |
Chromosome id | chr8 |
Chromosome position | 17534848 |
Reported gene | SLC7A2 |
Mapped gene | SLC7A2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6542 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2720499-? |
SNPs | rs2720499 |
Merged | |
SNP id current | 2720499 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (Recessive model) |
Or beta | 2.42 |
%95 Ci | unit decrease |
Platform | Illumina [542562] |
CNV | N |
Mapped trait | FEV change measurement, response to zileuton, asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST002951 |