SNP Detail For rs2698530
1.Mapping Information
Human SNP ID rs2698530
Human chromosome chr2
Human SNP position 64276761
Pig chromosome chr3
Pig SNP position 81468253
2.Annotation Information
PubMed ID21483845
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/21483845
StudyGenome-wide association study identifies genetic loci associated with iron deficiency.
Disease/TraitIron status biomarkers
Initial sample336 European ancestry iron deficiency cases, 343 European ancestry controls
Replication sample71 European ancestry iron deficiency cases, 161 European ancestry controls
Region2p14
Chromosome idchr2
Chromosome position64276761
Reported geneintergenic
Mapped geneLOC100507006 - LOC105374768
Upstream gene id100507006
Downstream gene id105374768
SNP gene ids
Upstream gene distance24230
Downstream gene distance26108
SNP risk allelers2698530-C
SNPsrs2698530
Merged0
SNP id current2698530
Contextregulatory_region_variant
Intergenic1
Allele frequencyNR
P value0.000004
Pvalue mlog5.39794000867203
P value text(Transferrin saturation)
Or beta20
%95 Ci[NR] unit decrease
PlatformIllumina [331060]
CNVN
Mapped traitanemia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004272
Study accessionGCST001021
PubMed ID21483845
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/21483845
StudyGenome-wide association study identifies genetic loci associated with iron deficiency.
Disease/TraitIron status biomarkers
Initial sample336 European ancestry iron deficiency cases, 343 European ancestry controls
Replication sample71 European ancestry iron deficiency cases, 161 European ancestry controls
Region2p14
Chromosome idchr2
Chromosome position64276761
Reported geneintergenic
Mapped geneLOC100507006 - LOC105374768
Upstream gene id100507006
Downstream gene id105374768
SNP gene ids
Upstream gene distance24230
Downstream gene distance26108
SNP risk allelers2698530-C
SNPsrs2698530
Merged0
SNP id current2698530
Contextregulatory_region_variant
Intergenic1
Allele frequencyNR
P value0.0000002
Pvalue mlog6.69897000433601
P value text(Total iron-binding capacity)
Or beta20.72
%95 Ci[NR] ug/dL increase
PlatformIllumina [331060]
CNVN
Mapped traitanemia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004272
Study accessionGCST001021
PubMed ID21483845
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/21483845
StudyGenome-wide association study identifies genetic loci associated with iron deficiency.
Disease/TraitIron status biomarkers
Initial sample336 European ancestry iron deficiency cases, 343 European ancestry controls
Replication sample71 European ancestry iron deficiency cases, 161 European ancestry controls
Region2p14
Chromosome idchr2
Chromosome position64276761
Reported geneintergenic
Mapped geneLOC100507006 - LOC105374768
Upstream gene id100507006
Downstream gene id105374768
SNP gene ids
Upstream gene distance24230
Downstream gene distance26108
SNP risk allelers2698530-C
SNPsrs2698530
Merged0
SNP id current2698530
Contextregulatory_region_variant
Intergenic1
Allele frequencyNR
P value0.0000001
Pvalue mlog7
P value text(Unsaturated iron-binding capacity)
Or beta28.75
%95 Ci[NR] ug/dL increase
PlatformIllumina [331060]
CNVN
Mapped traitanemia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004272
Study accessionGCST001021