SNP Detail For rs2634074
1.Mapping Information
Human SNP ID rs2634074
Human chromosome chr4
Human SNP position 110755885
Pig chromosome chr8
Pig SNP position 119772947
2.Annotation Information
PubMed ID26708676
JournalLancet Neurol
Linkwww.ncbi.nlm.nih.gov/pubmed/26708676
StudyLoci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.
Disease/TraitIschemic stroke
Initial sample14,300 European ancestry cases, 1,609 African ancestry cases, 942 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls
Replication sample996 African ancestry cases, 219 East Asian ancestry cases, 17,334 European ancestry cases, 548 Hispanic cases, 2,385 South Asian ancestry cases, 5,811 African ancestry controls, 329 East Asian ancestry controls, 350,928 European ancestry controls, 686 His
Region4q25
Chromosome idchr4
Chromosome position110755885
Reported genePITX2
Mapped genePITX2 - MIR297
Upstream gene id5308
Downstream gene id100126354
SNP gene ids
Upstream gene distance113762
Downstream gene distance104697
SNP risk allelers2634074-T
SNPsrs2634074
Merged0
SNP id current2634074
Contextintergenic_variant
Intergenic1
Allele frequency0.021
P value0.00000000000003
Pvalue mlog13.5228787452803
P value text
Or beta1.1
%95 Ci[1.07-1.12]
PlatformIllumina [up to 15400000] (imputed)
CNVN
Mapped traitIschemic stroke
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0002140
Study accessionGCST003258