SNP Detail For rs2614463
1.Mapping Information
Human SNP ID rs2614463
Human chromosome chr14
Human SNP position 99279937
Pig chromosome chr7
Pig SNP position 127863868
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region14q32.2
Chromosome idchr14
Chromosome position99279937
Reported geneNR
Mapped geneBCL11B - LOC105370660
Upstream gene id64919
Downstream gene id105370660
SNP gene ids
Upstream gene distance8224
Downstream gene distance5237
SNP risk allelers2614463-T
SNPsrs2614463
Merged0
SNP id current2614463
Contextintergenic_variant
Intergenic1
Allele frequency0.396310788487282
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP39)
Or beta0.1731
%95 Ci[0.098-0.249] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848