SNP Detail For rs2593149
1.Mapping Information
Human SNP ID rs2593149
Human chromosome chr10
Human SNP position 78630510
Pig chromosome chr14
Pig SNP position 87666725
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region10q22.3
Chromosome idchr10
Chromosome position78630510
Reported geneIntergenic
Mapped geneLOC105378378 - LOC105378379
Upstream gene id105378378
Downstream gene id105378379
SNP gene ids
Upstream gene distance156563
Downstream gene distance2010
SNP risk allelers2593149-T
SNPsrs2593149
Merged0
SNP id current2593149
Contextintron_variant
Intergenic1
Allele frequency0.694
P value0.0000006
Pvalue mlog6.22184874961635
P value text(AA)
Or beta0.018
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264