SNP Detail For rs2531995
1.Mapping Information
Human SNP ID rs2531995
Human chromosome chr16
Human SNP position 3963466
Pig chromosome chr3
Pig SNP position 39474859
2.Annotation Information
PubMed ID23563607
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23563607
StudyGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Disease/TraitObesity
Initial sample93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls
Replication sample65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls
Region16p13.3
Chromosome idchr16
Chromosome position3963466
Reported geneADCY9
Mapped geneADCY9
Upstream gene id
Downstream gene id
SNP gene ids115
Upstream gene distance
Downstream gene distance
SNP risk allelers2531995-T
SNPsrs2531995
Merged0
SNP id current2531995
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.61
P value0.00000004
Pvalue mlog7.39794000867203
P value text(Obesity I)
Or beta1.07
%95 Ci[NR]
PlatformAffymetrix, Illumina [~ 2800000] (imputed)
CNVN
Mapped traitobesity
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001073
Study accessionGCST001953
PubMed ID24861553
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24861553
StudyMeta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
Disease/TraitBody mass index
Initial sample82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals
Replication sampleUp to 47,352 East Asian ancestry individuals
Region16p13.3
Chromosome idchr16
Chromosome position3963466
Reported geneADCY9
Mapped geneADCY9
Upstream gene id
Downstream gene id
SNP gene ids115
Upstream gene distance
Downstream gene distance
SNP risk allelers2531995-T
SNPsrs2531995
Merged0
SNP id current2531995
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.33
P value0.00000007
Pvalue mlog7.15490195998574
P value text
Or beta0.0315
%95 Ci[0.02-0.043] unit increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002461