SNP Detail For rs2519974
1.Mapping Information
Human SNP ID rs2519974
Human chromosome chr16
Human SNP position 22877865
Pig chromosome chr3
Pig SNP position 23738974
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)
Initial sample168 Japanese ancestry cases, 335 Japanese ancestry controls
Replication sampleNA
Region16p12.2
Chromosome idchr16
Chromosome position22877865
Reported geneHS3ST2
Mapped geneHS3ST2
Upstream gene id
Downstream gene id
SNP gene ids9956
Upstream gene distance
Downstream gene distance
SNP risk allelers2519974-T
SNPsrs2519974
Merged0
SNP id current2519974
Contextintron_variant
Intergenic0
Allele frequency0.381
P value0.000004
Pvalue mlog5.39794000867203
P value text(Dominant model)
Or beta1.647
%95 Ci[1.264-2.146]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to cyclophosphamide, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1902518, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002002