Human SNP ID | rs2519974 |
---|---|
Human chromosome | chr16 |
Human SNP position | 22877865 |
Pig chromosome | chr3 |
Pig SNP position | 23738974 |
PubMed ID | 23648065 |
---|---|
Journal | Cancer Sci |
Link | www.ncbi.nlm.nih.gov/pubmed/23648065 |
Study | Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. |
Disease/Trait | Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide) |
Initial sample | 168 Japanese ancestry cases, 335 Japanese ancestry controls |
Replication sample | NA |
Region | 16p12.2 |
Chromosome id | chr16 |
Chromosome position | 22877865 |
Reported gene | HS3ST2 |
Mapped gene | HS3ST2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9956 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2519974-T |
SNPs | rs2519974 |
Merged | 0 |
SNP id current | 2519974 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.381 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (Dominant model) |
Or beta | 1.647 |
%95 Ci | [1.264-2.146] |
Platform | Illumina [733202] |
CNV | N |
Mapped trait | response to cyclophosphamide, response to antineoplastic agent |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_1902518, http://purl.obolibrary.org/obo/GO_0097327 |
Study accession | GCST002002 |