SNP Detail For rs2488856
1.Mapping Information
Human SNP ID rs2488856
Human chromosome chr14
Human SNP position 43062199
Pig chromosome chr1
Pig SNP position 192852340
2.Annotation Information
PubMed ID25080503
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25080503
StudyMeta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels.
Disease/TraitOsteoprotegerin levels
Initial sample4,158 European ancestry males, 531 South Tyrol males, 4,253 European ancestry females, 692 South Tyrol females, 702 Han Chinese ancestry females
Replication sampleNA
Region14q21.2
Chromosome idchr14
Chromosome position43062199
Reported geneintergenic
Mapped geneLRFN5 - LOC105370470
Upstream gene id145581
Downstream gene id105370470
SNP gene ids
Upstream gene distance1157650
Downstream gene distance246482
SNP risk allelers2488856-A
SNPsrs2488856
Merged0
SNP id current2488856
Contextintergenic_variant
Intergenic1
Allele frequency0.898
P value0.00000005
Pvalue mlog7.30102999566398
P value text(Sex-combined)
Or beta0.044
%95 Ci[0.028-0.060] unit decrease
PlatformAffymetrix, Illumina [up to 2544063] (imputed)
CNVN
Mapped traitosteoprotegerin measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005918
Study accessionGCST002546