Human SNP ID | rs2457996 |
---|---|
Human chromosome | chr4 |
Human SNP position | 73990818 |
Pig chromosome | chr8 |
Pig SNP position | 74170040 |
PubMed ID | 26192919 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,968 European ancestry cases, 20,464 European ancestry controls |
Replication sample | 10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 4q13.3 |
Chromosome id | chr4 |
Chromosome position | 73990818 |
Reported gene | NR |
Mapped gene | PPBP - CXCL5 |
Upstream gene id | 5473 |
Downstream gene id | 6374 |
SNP gene ids | |
Upstream gene distance | 2628 |
Downstream gene distance | 4824 |
SNP risk allele | rs2457996-A |
SNPs | rs2457996 |
Merged | |
SNP id current | 2457996 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.89 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (EA) |
Or beta | 1.1094414 |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST003045 |