Human SNP ID | rs2431697 |
---|---|
Human chromosome | chr5 |
Human SNP position | 160452971 |
Pig chromosome | chr16 |
Pig SNP position | 68426188 |
PubMed ID | 21408207 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21408207 |
Study | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls |
Replication sample | NA |
Region | 5q33.3 |
Chromosome id | chr5 |
Chromosome position | 160452971 |
Reported gene | PTTG1 |
Mapped gene | PTTG1 - MIR3142 |
Upstream gene id | 9232 |
Downstream gene id | 100422938 |
SNP gene ids | |
Upstream gene distance | 24227 |
Downstream gene distance | 21473 |
SNP risk allele | rs2431697-? |
SNPs | rs2431697 |
Merged | 0 |
SNP id current | 2431697 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.56 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (anti-dsDNA +) |
Or beta | 1.32 |
%95 Ci | [1.18-1.47] |
Platform | Illumina [421318] (imputed) |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST000996 |
PubMed ID | 26502338 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26502338 |
Study | Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 5,201 European ancestry cases, 9,066 European ancestry controls |
Replication sample | 2,018 European ancestry cases, 6,925 European ancestry controls |
Region | 5q33.3 |
Chromosome id | chr5 |
Chromosome position | 160452971 |
Reported gene | MIR146A |
Mapped gene | PTTG1 - MIR3142 |
Upstream gene id | 9232 |
Downstream gene id | 100422938 |
SNP gene ids | |
Upstream gene distance | 24227 |
Downstream gene distance | 21473 |
SNP risk allele | rs2431697-T |
SNPs | rs2431697 |
Merged | 0 |
SNP id current | 2431697 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | |
P value | 8E-28 |
Pvalue mlog | 27.096910013008 |
P value text | |
Or beta | 1.26 |
%95 Ci | [1.21鈥?.31] |
Platform | Illumina [644674] |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST003155 |