SNP Detail For rs2412459
1.Mapping Information
Human SNP ID rs2412459
Human chromosome chr15
Human SNP position 40003758
Pig chromosome chr1
Pig SNP position 146437554
2.Annotation Information
PubMed ID24751813
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/24751813
StudyGenome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment.
Disease/TraitResponse to haloperidol in psychosis
Initial sample96 European ancestry cases
Replication sampleNA
Region15q15.1
Chromosome idchr15
Chromosome position40003758
Reported geneEIF2AK4
Mapped geneEIF2AK4
Upstream gene id
Downstream gene id
SNP gene ids440275
Upstream gene distance
Downstream gene distance
SNP risk allelers2412459-C
SNPsrs2412459
Merged0
SNP id current2412459
Contextintron_variant
Intergenic0
Allele frequency0.218
P value0.000009
Pvalue mlog5.04575749056067
P value text(Total PANSS scores)
Or beta
%95 Ci
PlatformIllumina [1080870] (imputed)
CNVN
Mapped traitpsychosis, response to haloperidol
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005407, http://purl.obolibrary.org/obo/GO_1905119
Study accessionGCST002465