Human SNP ID | rs2310173 |
---|---|
Human chromosome | chr2 |
Human SNP position | 102047167 |
Pig chromosome | chr3 |
Pig SNP position | 54882629 |
PubMed ID | 21297633 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21297633 |
Study | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,687 European ancestry cases, 19,718 European ancestry controls |
Replication sample | 9,628 European ancestry cases, 12,917 European ancestry controls |
Region | 2q11.2 |
Chromosome id | chr2 |
Chromosome position | 102047167 |
Reported gene | IL1R2 |
Mapped gene | IL1R2 - LOC105373515 |
Upstream gene id | 7850 |
Downstream gene id | 105373515 |
SNP gene ids | |
Upstream gene distance | 18623 |
Downstream gene distance | 16639 |
SNP risk allele | rs2310173-T |
SNPs | rs2310173 |
Merged | 0 |
SNP id current | 2310173 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.46 |
P value | 0.000000000003 |
Pvalue mlog | 11.5228787452803 |
P value text | |
Or beta | 1.09 |
%95 Ci | [1.05-1.14] |
Platform | Affymetrix, Illumina [~ 1100000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000964 |
PubMed ID | 20062062 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20062062 |
Study | Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. |
Disease/Trait | Ankylosing spondylitis |
Initial sample | 2,053 European ancestry cases, 5,140 European ancestry controls |
Replication sample | 898 European ancestry cases, 1,518 European ancestry controls |
Region | 2q11.2 |
Chromosome id | chr2 |
Chromosome position | 102047167 |
Reported gene | IL1R2 |
Mapped gene | IL1R2 - LOC105373515 |
Upstream gene id | 7850 |
Downstream gene id | 105373515 |
SNP gene ids | |
Upstream gene distance | 18623 |
Downstream gene distance | 16639 |
SNP risk allele | rs2310173-A |
SNPs | rs2310173 |
Merged | 0 |
SNP id current | 2310173 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.45 |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | |
Or beta | 1.18 |
%95 Ci | [1.10-1.27] |
Platform | Illumina [288662] |
CNV | N |
Mapped trait | ankylosing spondylitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003898 |
Study accession | GCST000563 |
PubMed ID | 23453885 |
Journal | Lancet |
Link | www.ncbi.nlm.nih.gov/pubmed/23453885 |
Study | Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. |
Disease/Trait | Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) |
Initial sample | 6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder tr |
Replication sample | NA |
Region | 2q11.2 |
Chromosome id | chr2 |
Chromosome position | 102047167 |
Reported gene | MAP4K4, IL1R2 |
Mapped gene | IL1R2 - LOC105373515 |
Upstream gene id | 7850 |
Downstream gene id | 105373515 |
SNP gene ids | |
Upstream gene distance | 18623 |
Downstream gene distance | 16639 |
SNP risk allele | rs2310173-T |
SNPs | rs2310173 |
Merged | 0 |
SNP id current | 2310173 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (Modelling analysis) |
Or beta | 1.06 |
%95 Ci | [1.03-1.08] |
Platform | NR [1252901] (imputed) |
CNV | N |
Mapped trait | attention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 |
Study accession | GCST001877 |