SNP Detail For rs2307449
1.Mapping Information
Human SNP ID rs2307449
Human chromosome chr15
Human SNP position 89320697
Pig chromosome chr7
Pig SNP position 59868702
2.Annotation Information
PubMed ID22267201
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22267201
StudyMeta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
Disease/TraitMenopause (age at onset)
Initial sample38,968 European ancestry female individuals
Replication sampleUp to 14,435 European ancestry female individuals
Region15q26.1
Chromosome idchr15
Chromosome position89320697
Reported genePOLG
Mapped genePOLG
Upstream gene id
Downstream gene id
SNP gene ids5428
Upstream gene distance
Downstream gene distance
SNP risk allelers2307449-G
SNPsrs2307449
Merged0
SNP id current2307449
Contextintron_variant
Intergenic0
Allele frequency0.405
P value0.0000000000004
Pvalue mlog12.397940008672
P value text
Or beta0.184
%95 Ci[0.14-0.23] years decrease
PlatformAffymetrix, Illumina [2551160] (imputed)
CNVN
Mapped traitage at menopause
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004704
Study accessionGCST001381