Human SNP ID | rs2307449 |
---|---|
Human chromosome | chr15 |
Human SNP position | 89320697 |
Pig chromosome | chr7 |
Pig SNP position | 59868702 |
PubMed ID | 22267201 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22267201 |
Study | Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. |
Disease/Trait | Menopause (age at onset) |
Initial sample | 38,968 European ancestry female individuals |
Replication sample | Up to 14,435 European ancestry female individuals |
Region | 15q26.1 |
Chromosome id | chr15 |
Chromosome position | 89320697 |
Reported gene | POLG |
Mapped gene | POLG |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5428 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2307449-G |
SNPs | rs2307449 |
Merged | 0 |
SNP id current | 2307449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.405 |
P value | 0.0000000000004 |
Pvalue mlog | 12.397940008672 |
P value text | |
Or beta | 0.184 |
%95 Ci | [0.14-0.23] years decrease |
Platform | Affymetrix, Illumina [2551160] (imputed) |
CNV | N |
Mapped trait | age at menopause |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004704 |
Study accession | GCST001381 |