Human SNP ID | rs2302045 |
---|---|
Human chromosome | chr2 |
Human SNP position | 241081801 |
Pig chromosome | chr15 |
Pig SNP position | 154988002 |
PubMed ID | 25944848 |
---|---|
Journal | J Psychopharmacol |
Link | www.ncbi.nlm.nih.gov/pubmed/25944848 |
Study | Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs. |
Disease/Trait | Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio) |
Initial sample | Up to 829 European ancestry cases |
Replication sample | NA |
Region | 2q37.3 |
Chromosome id | chr2 |
Chromosome position | 241081801 |
Reported gene | SNED1 |
Mapped gene | MTERF4, SNED1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 130916, 25992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2302045-T |
SNPs | rs2302045 |
Merged | |
SNP id current | 2302045 |
Context | splice_region_variant |
Intergenic | 0 |
Allele frequency | 0.067 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | |
Or beta | 0.4064 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix [686595] |
CNV | N |
Mapped trait | unipolar depression, schizophrenia, bipolar disorder, concentration dose ratio, response to antipsychotic drug |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0007635, http://purl.obolibrary.org/obo/GO_0097332 |
Study accession | GCST002888 |