SNP Detail For rs2301659
1.Mapping Information
Human SNP ID rs2301659
Human chromosome chr19
Human SNP position 18924545
Pig chromosome chr2
Pig SNP position 58724928
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal P-tau181p levels
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region19p13.11
Chromosome idchr19
Chromosome position18924545
Reported geneDDX49
Mapped geneDDX49
Upstream gene id
Downstream gene id
SNP gene ids54555
Upstream gene distance
Downstream gene distance
SNP risk allelers2301659-G
SNPsrs2301659
Merged
SNP id current2301659
Contextintron_variant
Intergenic0
Allele frequency0.32
P value0.000003
Pvalue mlog5.52287874528033
P value text
Or beta0.1186
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitp-tau measurement, cerebrospinal fluid biomarker measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004763, http://www.ebi.ac.uk/efo/EFO_0006794
Study accessionGCST003071
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal fluid p-Tau181p:AB1-42 ratio
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region19p13.11
Chromosome idchr19
Chromosome position18924545
Reported geneDDX49
Mapped geneDDX49
Upstream gene id
Downstream gene id
SNP gene ids54555
Upstream gene distance
Downstream gene distance
SNP risk allelers2301659-G
SNPsrs2301659
Merged
SNP id current2301659
Contextintron_variant
Intergenic0
Allele frequency0.32
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta0.1679
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitp-tau:beta-amyloid 1-42 ratio measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007709
Study accessionGCST003078