SNP Detail For rs2293889
1.Mapping Information
Human SNP ID rs2293889
Human chromosome chr8
Human SNP position 115586972
Pig chromosome chr4
Pig SNP position 24839882
2.Annotation Information
PubMed ID20686565
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/20686565
StudyBiological, clinical and population relevance of 95 loci for blood lipids.
Disease/TraitHDL cholesterol
Initial sample99,900 European ancestry individuals
Replication sampleNA
Region8q23.3
Chromosome idchr8
Chromosome position115586972
Reported geneTRPS1
Mapped geneTRPS1
Upstream gene id
Downstream gene id
SNP gene ids7227
Upstream gene distance
Downstream gene distance
SNP risk allelers2293889-T
SNPsrs2293889
Merged0
SNP id current2293889
Contextintron_variant
Intergenic0
Allele frequency0.41
P value0.00000000006
Pvalue mlog10.2218487496163
P value text
Or beta0.44
%95 Ci[0.28-0.6] mg/dL decrease
PlatformAffymetrix, Illumina, Perlegen [~ 2600000] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST000755
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitHDL cholesterol
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region8q23.3
Chromosome idchr8
Chromosome position115586972
Reported geneTRPS1
Mapped geneTRPS1
Upstream gene id
Downstream gene id
SNP gene ids7227
Upstream gene distance
Downstream gene distance
SNP risk allelers2293889-T
SNPsrs2293889
Merged0
SNP id current2293889
Contextintron_variant
Intergenic0
Allele frequency0.41
P value0.00000000000000004
Pvalue mlog16.397940008672
P value text
Or beta0.031
%95 Ci[NR] unit decrease
PlatformNR [NR] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002223