SNP Detail For rs2286276
1.Mapping Information
Human SNP ID rs2286276
Human chromosome chr7
Human SNP position 73573024
Pig chromosome chr3
Pig SNP position 10588641
2.Annotation Information
PubMed ID21909109
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21909109
StudyLarge-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
Disease/TraitTriglycerides
Initial sample12,545 Korean ancestry individuals
Replication sampleUp to 30,395 East Asian ancestry individuals
Region7q11.23
Chromosome idchr7
Chromosome position73573024
Reported geneTBL2, MLXIPL
Mapped geneTBL2
Upstream gene id
Downstream gene id
SNP gene ids26608
Upstream gene distance
Downstream gene distance
SNP risk allelers2286276-T
SNPsrs2286276
Merged0
SNP id current2286276
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.1
P value0.000000000000001
Pvalue mlog15
P value text
Or beta0.0652
%95 Ci[0.049-0.081] mg/dL decrease
PlatformAffymetrix [~ 2200000] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST001230
PubMed ID23505323
JournalJ Med Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23505323
StudyGenomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
Disease/TraitHypertriglyceridemia
Initial sample1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls
Replication sample1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls
Region7q11.23
Chromosome idchr7
Chromosome position73573024
Reported geneTBL2, VPS37D, MLXIPL, BAZ1B, BCL7B
Mapped geneTBL2
Upstream gene id
Downstream gene id
SNP gene ids26608
Upstream gene distance
Downstream gene distance
SNP risk allelers2286276-?
SNPsrs2286276
Merged0
SNP id current2286276
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.88
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.39
%95 Ci[1.25-1.53]
PlatformIllumina [1361436] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST001905