SNP Detail For rs2278491
1.Mapping Information
Human SNP ID rs2278491
Human chromosome chr8
Human SNP position 116644632
Pig chromosome chr4
Pig SNP position 23449094
2.Annotation Information
PubMed ID25673413
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673413
StudyGenetic studies of body mass index yield new insights for obesity biology.
Disease/TraitBody mass index
Initial sampleup to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals
Replication sampleup to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828
Region8q23.3
Chromosome idchr8
Chromosome position116644632
Reported geneEIF3H
Mapped geneLOC105375712 - EIF3H
Upstream gene id105375712
Downstream gene id8667
SNP gene ids
Upstream gene distance29333
Downstream gene distance184
SNP risk allelers2278491-C
SNPsrs2278491
Merged0
SNP id current2278491
Context3_prime_UTR_variant
Intergenic1
Allele frequency0.878
P value0.000006
Pvalue mlog5.22184874961635
P value text(EA, men)
Or beta0.028
%95 Ci[0.016-0.04] kg/m2 increase
PlatformAffymetrix, Illumina [2550021]
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002783