SNP Detail For rs2277027
1.Mapping Information
Human SNP ID rs2277027
Human chromosome chr5
Human SNP position 157505368
Pig chromosome chr16
Pig SNP position 71631239
2.Annotation Information
PubMed ID20010835
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20010835
StudyMeta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Disease/TraitPulmonary function
Initial sample20,890 European ancestry individuals
Replication sample16,178 European ancestry individuals
Region5q33.3
Chromosome idchr5
Chromosome position157505368
Reported geneADAM19
Mapped geneADAM19
Upstream gene id
Downstream gene id
SNP gene ids8728
Upstream gene distance
Downstream gene distance
SNP risk allelers2277027-A
SNPsrs2277027
Merged0
SNP id current2277027
Contextintron_variant
Intergenic0
Allele frequency0.71
P value0.0000000001
Pvalue mlog10
P value text(FEV1/FVC)
Or beta0.38
%95 Ci[NR] % increase
PlatformAffymetrix, Illumina [2534500] (imputed)
CNVN
Mapped traitpulmonary function measurement, FEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST000542
PubMed ID23284291
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23284291
StudyGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Disease/TraitPulmonary function (interaction)
Initial sample50,047 European ancestry individuals
Replication sampleNA
Region5q33.3
Chromosome idchr5
Chromosome position157505368
Reported geneADAM19
Mapped geneADAM19
Upstream gene id
Downstream gene id
SNP gene ids8728
Upstream gene distance
Downstream gene distance
SNP risk allelers2277027-?
SNPsrs2277027
Merged0
SNP id current2277027
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000000002
Pvalue mlog10.698970004336
P value text(FEV1/FVC, Ever-smoking)
Or beta
%95 Ci
PlatformNR [~ 2500000] (imputed)
CNVN
Mapped traitFEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001784