Human SNP ID | rs2277027 |
---|---|
Human chromosome | chr5 |
Human SNP position | 157505368 |
Pig chromosome | chr16 |
Pig SNP position | 71631239 |
PubMed ID | 20010835 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20010835 |
Study | Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. |
Disease/Trait | Pulmonary function |
Initial sample | 20,890 European ancestry individuals |
Replication sample | 16,178 European ancestry individuals |
Region | 5q33.3 |
Chromosome id | chr5 |
Chromosome position | 157505368 |
Reported gene | ADAM19 |
Mapped gene | ADAM19 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8728 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2277027-A |
SNPs | rs2277027 |
Merged | 0 |
SNP id current | 2277027 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.71 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | (FEV1/FVC) |
Or beta | 0.38 |
%95 Ci | [NR] % increase |
Platform | Affymetrix, Illumina [2534500] (imputed) |
CNV | N |
Mapped trait | pulmonary function measurement, FEV/FEC ratio |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST000542 |
PubMed ID | 23284291 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23284291 |
Study | Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. |
Disease/Trait | Pulmonary function (interaction) |
Initial sample | 50,047 European ancestry individuals |
Replication sample | NA |
Region | 5q33.3 |
Chromosome id | chr5 |
Chromosome position | 157505368 |
Reported gene | ADAM19 |
Mapped gene | ADAM19 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8728 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2277027-? |
SNPs | rs2277027 |
Merged | 0 |
SNP id current | 2277027 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | (FEV1/FVC, Ever-smoking) |
Or beta | |
%95 Ci | |
Platform | NR [~ 2500000] (imputed) |
CNV | N |
Mapped trait | FEV/FEC ratio |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST001784 |