Human SNP ID | rs2276314 |
---|---|
Human chromosome | chr18 |
Human SNP position | 35977503 |
Pig chromosome | chr6 |
Pig SNP position | 112268986 |
PubMed ID | 24223155 |
---|---|
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/24223155 |
Study | Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. |
Disease/Trait | Drug-induced torsades de pointes |
Initial sample | 216 European ancestry cases, 386 European ancestry drug-exposed controls, 385 European ancestry population controls |
Replication sample | NA |
Region | 18q12.2 |
Chromosome id | chr18 |
Chromosome position | 35977503 |
Reported gene | C18orf21, RPRD1A, MIR187, GALNT1 |
Mapped gene | C18orf21 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 83608 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2276314-? |
SNPs | rs2276314 |
Merged | 0 |
SNP id current | 2276314 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (all controls combined) |
Or beta | 2 |
%95 Ci | [1.5-2.6] |
Platform | Illumina [3542142] (imputed) |
CNV | N |
Mapped trait | torsades de pointes, response to drug |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005307, http://purl.obolibrary.org/obo/GO_0042493 |
Study accession | GCST002269 |