Human SNP ID | rs2276109 |
---|---|
Human chromosome | chr11 |
Human SNP position | 102875061 |
Pig chromosome | chr9 |
Pig SNP position | 37431303 |
PubMed ID | 26634245 |
---|---|
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1 |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 11q22.2 |
Chromosome id | chr11 |
Chromosome position | 102875061 |
Reported gene | Intergenic |
Mapped gene | MMP12 - BOLA3P1 |
Upstream gene id | 4321 |
Downstream gene id | 100288111 |
SNP gene ids | |
Upstream gene distance | 27 |
Downstream gene distance | 5423 |
SNP risk allele | rs2276109-T |
SNPs | rs2276109 |
Merged | 0 |
SNP id current | 2276109 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.887 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 0.072 |
%95 Ci | NR unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume, response to bronchodilator |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 |
Study accession | GCST003262 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 11q22.2 |
Chromosome id | chr11 |
Chromosome position | 102875061 |
Reported gene | Intergenic |
Mapped gene | MMP12 - BOLA3P1 |
Upstream gene id | 4321 |
Downstream gene id | 100288111 |
SNP gene ids | |
Upstream gene distance | 27 |
Downstream gene distance | 5423 |
SNP risk allele | rs2276109-T |
SNPs | rs2276109 |
Merged | 0 |
SNP id current | 2276109 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.887 |
P value | 0.0000000007 |
Pvalue mlog | 9.15490195998574 |
P value text | |
Or beta | 0.019 |
%95 Ci | unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003264 |