SNP Detail For rs2274700
1.Mapping Information
Human SNP ID rs2274700
Human chromosome chr1
Human SNP position 196713817
Pig chromosome chr10
Pig SNP position 24385460
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region1q31.3
Chromosome idchr1
Chromosome position196713817
Reported geneCFH
Mapped geneCFH
Upstream gene id
Downstream gene id
SNP gene ids3075
Upstream gene distance
Downstream gene distance
SNP risk allelers2274700-A
SNPsrs2274700
Merged0
SNP id current2274700
Contextsynonymous_variant
Intergenic0
Allele frequency0.4
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta0.012
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003265