SNP Detail For rs2274316
1.Mapping Information
Human SNP ID rs2274316
Human chromosome chr1
Human SNP position 156476450
Pig chromosome chr4
Pig SNP position 102224867
2.Annotation Information
PubMed ID23793025
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23793025
StudyGenome-wide meta-analysis identifies new susceptibility loci for migraine.
Disease/TraitMigraine
Initial sample23,285 European ancestry cases, 95,425 European ancestry controls
Replication sampleNA
Region1q22
Chromosome idchr1
Chromosome position156476450
Reported geneMEF2D, APOA1BP
Mapped geneMEF2D
Upstream gene id
Downstream gene id
SNP gene ids4209
Upstream gene distance
Downstream gene distance
SNP risk allelers2274316-C
SNPsrs2274316
Merged0
SNP id current2274316
Contextintron_variant
Intergenic0
Allele frequency0.36
P value0.00000001
Pvalue mlog8
P value text
Or beta1.07
%95 Ci[1.05-1.10]
PlatformAffymetrix, Illumina [~ 2300000] (imputed)
CNVN
Mapped traitmigraine disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003821
Study accessionGCST002081
PubMed ID23793025
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23793025
StudyGenome-wide meta-analysis identifies new susceptibility loci for migraine.
Disease/TraitMigraine - clinic-based
Initial sample5,175 European ancestry clinic-based cases, 13,972 European ancestry clinic-based controls
Replication sampleNA
Region1q22
Chromosome idchr1
Chromosome position156476450
Reported geneMEF2D, APOA1BP
Mapped geneMEF2D
Upstream gene id
Downstream gene id
SNP gene ids4209
Upstream gene distance
Downstream gene distance
SNP risk allelers2274316-C
SNPsrs2274316
Merged0
SNP id current2274316
Contextintron_variant
Intergenic0
Allele frequency0.36
P value0.0000001
Pvalue mlog7
P value text
Or beta1.14
%95 Ci[1.09-1.20]
PlatformAffymetrix, Illumina [~ 2300000] (imputed)
CNVN
Mapped traitmigraine disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003821
Study accessionGCST002079