Human SNP ID | rs2274223 |
---|---|
Human chromosome | chr10 |
Human SNP position | 94306584 |
Pig chromosome | chr14 |
Pig SNP position | 115594086 |
PubMed ID | 21642993 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21642993 |
Study | Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. |
Disease/Trait | Esophageal cancer |
Initial sample | 2,031 Han Chinese ancestry cases, 2,044 Han Chinese ancestry controls |
Replication sample | 3,986 Han Chinese ancestry cases, 4,157 Han Chinese ancestry controls |
Region | 10q23.33 |
Chromosome id | chr10 |
Chromosome position | 94306584 |
Reported gene | PLCE1 |
Mapped gene | PLCE1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51196 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2274223-G |
SNPs | rs2274223 |
Merged | 0 |
SNP id current | 2274223 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.21 |
P value | 4E-20 |
Pvalue mlog | 19.397940008672 |
P value text | |
Or beta | 1.34 |
%95 Ci | [1.26-1.42] |
Platform | Affymetrix [666141] |
CNV | N |
Mapped trait | esophageal carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002916 |
Study accession | GCST001089 |
PubMed ID | 25129146 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25129146 |
Study | Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. |
Disease/Trait | Esophageal squamous cell carcinoma |
Initial sample | 5,337 Han Chinese ancestry cases, 5,787 Han Chinese ancestry controls |
Replication sample | 9,654 Han Chinese ancestry cases, 10,058 Han Chinese ancestry controls |
Region | 10q23.33 |
Chromosome id | chr10 |
Chromosome position | 94306584 |
Reported gene | PLCE1, KIAA1516 |
Mapped gene | PLCE1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51196 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2274223-G |
SNPs | rs2274223 |
Merged | 0 |
SNP id current | 2274223 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.209 |
P value | 0.000000000000000004 |
Pvalue mlog | 17.397940008672 |
P value text | |
Or beta | 1.35 |
%95 Ci | [1.26-1.45] |
Platform | Affymetrix, Illumina [7556215] (imputed) |
CNV | N |
Mapped trait | esophageal squamous cell carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005922 |
Study accession | GCST002568 |