SNP Detail For rs2273359
1.Mapping Information
Human SNP ID rs2273359
Human chromosome chr20
Human SNP position 58987047
Pig chromosome chr17
Pig SNP position 66504413
2.Annotation Information
PubMed ID23753411
JournalHypertension
Linkwww.ncbi.nlm.nih.gov/pubmed/23753411
StudyGenomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
Disease/TraitResponse to diuretic therapy in hypertension
Initial sample424 European ancestry individuals
Replication sample841 European ancestry individuals
Region20q13.32
Chromosome idchr20
Chromosome position58987047
Reported geneTH1L, EDN3, GNAS
Mapped geneNELFCD
Upstream gene id
Downstream gene id
SNP gene ids51497
Upstream gene distance
Downstream gene distance
SNP risk allelers2273359-C
SNPsrs2273359
Merged0
SNP id current2273359
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.04
P value0.00000006
Pvalue mlog7.22184874961635
P value text
Or beta8.15
%95 Ci[NR] mm Hg increase
PlatformIllumina [1092841] (imputed)
CNVN
Mapped traitresponse to diruetic
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036270
Study accessionGCST002067