Human SNP ID | rs2273359 |
---|---|
Human chromosome | chr20 |
Human SNP position | 58987047 |
Pig chromosome | chr17 |
Pig SNP position | 66504413 |
PubMed ID | 23753411 |
---|---|
Journal | Hypertension |
Link | www.ncbi.nlm.nih.gov/pubmed/23753411 |
Study | Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. |
Disease/Trait | Response to diuretic therapy in hypertension |
Initial sample | 424 European ancestry individuals |
Replication sample | 841 European ancestry individuals |
Region | 20q13.32 |
Chromosome id | chr20 |
Chromosome position | 58987047 |
Reported gene | TH1L, EDN3, GNAS |
Mapped gene | NELFCD |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 51497 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2273359-C |
SNPs | rs2273359 |
Merged | 0 |
SNP id current | 2273359 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.04 |
P value | 0.00000006 |
Pvalue mlog | 7.22184874961635 |
P value text | |
Or beta | 8.15 |
%95 Ci | [NR] mm Hg increase |
Platform | Illumina [1092841] (imputed) |
CNV | N |
Mapped trait | response to diruetic |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0036270 |
Study accession | GCST002067 |